Studio : dr best

Publisher : dr best

Binding : Health and Beauty

Product Description
5HTP functions as the precursor for serotonin, a monoamine neurotransmitter found in the central nervous system (CNS) and some cells of the digestive tract. In the body, 5HTP is formed by the addition of a hydroxyl group (OH) to tryptophan, a reaction catalyzed by the enzyme tryptophan hydroxylase. This enzyme can be hindered by stress and conditions such as vitamin B6 deficiency, which is one reason B6 is included in this formula. Additionally, pyridoxal phosphate (vitamin B6) is necessary for 5HTP to be converted to serotonin. Vitamin C participates in the conversion of tryptophan to 5HTP and of tyrosine to norepinephrine, another important neurotransmitter. Synthesis of serotonin in the brain requires an adequate supply of either tryptophan or 5HTP as precursors in the CNS. The supply of tryptophan available for conversion to 5HTP depends on a number of factors, including the nutritional status of the individual and the competition between tryptophan and other amino acids for transport across the bloodbrain barrier. Whereas tryptophan may be sidetracked into the production of niacin or protein, 5HTP readily crosses the bloodbrain barrier and becomes available for serotonin synthesis. Therefore, supplementation with 5HTP is a more direct route to serotonin production.
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