Fem-Dophilus contains 2 patented and clinically documents probiotic strains, Lactobacillus Rhamnosus, GR-1 and Lactobacillus Reuteri, RC-14, discovered and developed by Dr. Gregor Reid and Dr. Andrew Bruce at Urex Biotech.over 25 years of research supports the oral use of GR-1 and RC-14 to colonize and promote healthy vaginal and urinary tract health.*A special manufacturing process helps protect the probiotic strains in Fem-Dophilus from stomach acid and promotes probiotic bacterial survival to the lower intestine.Expiration04/03/2019