Citrulline Malate is a commonly found ingredient in pre-workout formulas, consisting of a unique combination of the amino acid citrulline and the organic salt malate. Citrulline Malate is a pre cursor to Arginine, and increases Nitric oxide (NO) production by increasing blood arginine levels. NO is responsible for vasodilation (expanding of the blood vessels), which leads to increased blood flow to muscles during exercise, which in turn allows them to last longer under work, and produce bigger muscle pumps to weightlifters. Citrulline malate also aids in the removal of toxins such as lactic acid and ammonia, which are by-products of intense physical activity, protein metabolism and catabolic states.