A riveting medical mystery about a young womans quest to uncover the truth about her likely fatal genetic disorder that opens a window onto the exploding field of genomic medicine

When Joselin Linder was in her twenties her legs suddenly started to swell. After years of misdiagnoses doctors discovered a deadly blockage in her liver. Struggling to find ?an explanation for her unusual condition Joselin compared the medical chart of her fatherwho had died from a mysterious disease ten years priorwith that of an uncle who had died under similarly strange circumstances. Delving further into the past she discovered that her great-grandmother had displayed symptoms similar to hers before her death. Clearly this was more than a fluke.

Setting out to build a more complete picture of the illness that haunted her family Joselin approached Dr. Christine Seidman the head of a group of world-class genetic researchers at Harvard Medical School for help. Dr. Seidman had been working on her familys case for twenty years and had finally confirmed that fourt