How to Use 1) For external use only. Do not apply around eyes, mucous membrane, skin with eczema or rash, and wound.Do not use on mucous membrans,wounds,rashes and damaged skin,face,area where topical medication has been applied. 2) Consult a doctor or pharmacist before using if you ever experienced an allergic/hypersensitive reaction to products for external use such as drugs or cosmetics. 3) Do not use on children 12 years and under, do not use heat patch in conjunction with other creams, rubs or lotions applied to the skin or with/near to other heat sources. 4) Use the products immediately upon opening the pack, as product will produce heat upon opening. 5) Do not use the product for more than 10 hours in a day. 6) Each patch is for single use.