Polar opposites Qin (Francis Ng), a surgeon, and Wen (Zhang Dan Feng), a Chinese medicine practitioner, are made to work together to treat underprivileged patients in a traditional Chinese medicine clinic. An unexpected crisis sees the loggerheads form a friendship that transcends prejudices and superstitions, and learn that the greatest medicine is love and compassion.

两个性格迥然不同的年轻医师 - 习西医的秦火（吴镇宇）和习中医的温游（张丹峰）在中医医院院长的安排下以中西理论来治病。而这对冤家在一场疫症爆发下渐渐建立起友谊，并同心协力，以中西医合并的治疗方法成功地挽救面临封院的医院，更让他们明白医者父母心的道理。