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Outline

Leukoplakia Oral
Leukoplakia Oral
China\'s "two-disease" (oral leukoplakia and oral) prevention study group in 1983, according to who\'s revised definition of the olk occurred in the oral mucosa keratosis white patches, the formation of lesions, not including smoking local irritation. Factors can be dissipated through the simple keratosis. the defined two points: 1. Clear that the olk is a formation of lesion; II expressly zero by the local physical and chemical factors stimulation of a large class of white keratoses.
Currently, most scholars believe OLK over and oral benign keratoses (oralbenignhyperkemtosis, OHK) are two totally different nature white oral mucosal damage. The former is precancerous lesions, with varying degrees of dysplasia the latter is a benign; lesion, had keratosis, but no dysplasia, with clear risk factors, such as smoking, after the removal of the cause, the damage can be reversed We should strictly distinguish between. The two, in order to facilitate the guidance of research and clinical work, but also eased the majority white keratosis patient\'s mental burden, increased awareness of OLK vigilance.
Pathogenesis
Stimulation of local Long-term factors and the incidence of oral leukoplakia and certain systemic factors.
1 and Smoking other physical and chemical stimuli
Epidemiological surveys show that the incidence of smoking and duration of smoking history and a positive correlation between the spot, the number of cigarettes smoked per day * years of smoking> 400 years increasing the risk of, occurrence of white spots. In addition to the different types of tobacco products, the incidence of low white there are differences, which in descending order are: pipe down> cigarette> hookah domestic scholars extract was applied; directly to the mucous membrane irritation with cigarettes or tobacco smoke and can be prepared white animal model, confirming the close relationship between smoking and the incidence of vitiligo.
Drinking alcohol Like eating too hot or sour food chewing betel nut and other local physical and chemical stimulation related to leukoplakia..
2 infections Candida
Epidemiological surveys show that oral leukoplakia patients, Candida albicans was detected in about 34%, which in addition to Candida albicans, the star may be associated with Candida tropicalis and Candida leukoplakia occurrence are closely linked. at the same time it is certain that the infection with Candida albicans is white, "white spot read" prone to malignant.
3 factors systemic
Including trace elements (including manganese Mn, Sr strontium, calcium (CA) and microcirculation changes of susceptibility genetic predisposition, lack of and the like, fat-soluble vitamins (vitamin A deficiency causes epithelial hyperkeratosis)
Manifestations Clinical
A). Manifestations olk mainly appear white patchy lesions on one or multiple oral mucosa, can occur in any part of the oral mucosa, but the cheek, tongue, and most common. Because the clinical manifestations of vitiligo changes, and its various manifestations treatment and prognosis are not the same, in order to facilitate the diagnosis, treatment and observation, it is necessary to do meticulous white type or classification.
For classification of vitiligo, scholars over the years there have been a number of different classification methods. Banaczy the olk local performance divied into simple, warty type and ulcer type III; Pinborg advocated olk divied into two homogenous and granular type, and domestic Li copy will olk into plaque into the type, like the crepe paper and warty type 4 type.
China\'s "two-disease" cooperative group studies comprehensive all aspects of the OLK divided into the following 4 types:
1 Simplex (known as also type homogeneous) white patches as the surface is slightly rough crepe paper-like or grooved asymptomatic or mild discomfort..
2 type warty milky white thick high and the surface uneven thorn-like villous or rough projections slightly harder quality may have discomfort..
3 on granule congestion or redness of membrane mucous the white particles of varying sizes keratosis or nodular mucosal surface above may be associated with erosion pain and irritation can occur.
4 type Ulcer on a white plaque erosions or ulcers often accompanied by spontaneous pain.
From the above point of view the proportion of type 4 to type simple majority, followed by verrucous type, and particle type and ulcer type is less, and the homogeneous type, particle type and verrucous type are likely to assume into ulceration.

 

 

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