Product Information

Description
SAM-e Joint Promotes: Joint Strength*, Liver Detoxification*, Mood and Brain Function*
Jarrow Formulas SAM-e Joint provides a full 200 mg SAM-e (net yield) and 525 mg of glucosamine hydrochloride in every enteric-coated tablet. SAM-e Joint is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. SAM-e and glucosamine are known to benefit joint function and recuperation.
Contains More of the Active S,S Form SAM-e
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
Glucosamine
Glucosamine is an aminosaccharide synthesized by transamidase enzymes from glucose and an amine group from glutamine. HCl (hydrochloric acid) stabilizes the glucosamine in this product. Glucosamine is a component of joint and intestinal tissue and is involved in the production of synovial fluid that lubricates the joints.*

SAM-e has been clinically shown to have the following benefits:
Joint Strength
SAM-e supports the production of healthy connective tissue through transulfaration.* In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAM-e metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.*
Brain Metabolism
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine, and phosphatidylcholine (a component of lecithin).
Liver
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function, including phase II detoxification.*
Jarrow Formulas SAM-e Joint is Joint Sustain nutrition, providing glucosamine HCl, a sodium free form of glucosamine.
For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.

Label (click image to enlarge)

PRODUCT DIRECTIONS / ADDITIONAl INFO
Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.

Warnings
Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using this product. Individuals with Parkinson''s disease, bi-polar disorder or manic depression should not use SAM-e. Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use., Keep out of reach of children.

, Do not use if seal is broken or missing.

Other Ingredients
Cellulose, Glyceryl Behenate, medium chain triglycerides, Oleic Acid, sodium alginate, Titanium Dioxide, riboflavin, Stearic Acid (Vegetable Source), silicon dioxide, Magnesium Stearate (vegetable source) , Dextrin, dextrose, Sodium Citrate

Storage
Store in a cool, dry place.

Jarrow Formulas
Los Angeles, CA 90035-4317

Nutrition Facts

Serving Size? 1 Tablet(s)Servings Per Container? 60

Amount Per Serving? ? % DV

Glucosamine HCl? 525 mg ? **
S-adenosylmethionine (SAM-e)? 200 mg ? **

** Daily Value (DV) not established.